Fig. 2.

Identification of the Immune Infiltration-Related Expression Genes. (A) Heatmap displaying the top 15 immune-related differentially expressed genes, including IGJ, IGLL5, MMP12, SRGN, CCL18, APOE, C1QB, C1QC, CXCL10, CXCL9, HLA−DRB5, HLA−DRB1, HLA−DPB1, HLA−DRA, HLA−DPA1. The top bar represents the grouping information, and the central plot represents the gradient of normalized log2FPKM (fragments per kilobase of transcript per million mapped reads). (B) Volcano plot showing the differentially upregulated (red nodes) and downregulated genes (blue nodes) with log₂(fold change) > 2 and adjusted p value < 0.05 were labeled. (C) Gene set enrichment analysis (GSEA) shows the significant enrichment of 10 immune-related biological processes.