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. 2024 Jun 13;74:103230. doi: 10.1016/j.redox.2024.103230

Fig. 2.

Fig. 2

AKG pretreatment improves hepatic mitochondrial dysfunction in P407-induced hyperlipidemia mice. Liver (A) ATP content, (B) Relative mtDNA copy number, (C) Western blot image and (D) statistical analysis on relative protein content of complexes I–V in mouse liver, (E) Western blot image and (F) statistical analysis on relative protein content of PGC-1α, TFAM, Drp1, MFN1, MFN2, OPA1-L, OPA1-S in mouse liver, (G) Relative activity of mitochondrial complex I–V in hyperlipidemic mouse liver. The values are means ± SEM,c n = 6. *p < 0.05, **p < 0.01, and ***p < 0.001.