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. 2024 Jun 13;74:103230. doi: 10.1016/j.redox.2024.103230

Fig. 3.

Fig. 3

AKG pretreatment inhibits the loss of hepatic redox homeostasis in P407-induced hyperlipidemia mice. Liver (A) ROS, (B) LPO, (C) MDA, (D) protein carbonyl, (E) catalase activity, (F) total SOD activity, (G) SOD2 activity (H) and SOD1 activity. (I) Western blot image and (J) Statistical analysis on the relative protein content of Nrf2, Keap1, NQO1, Catalase, HO-1, SOD2, and SOD1 in the hyperlipidemic mouse liver. (K) Western blot image of SOD2 and AcSOD2, (L) statistical analysis on the relative protein content of AcSOD2/SOD2 in the liver. The values are means ± SEM, n = 6. *p < 0.05, **p < 0.01, and ***p < 0.001.