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. 2024 May 23;13(3):e230269. doi: 10.1530/ETJ-23-0269

Table 3.

Comparison of Chinese clinical practice guideline recommendations to survey responses.

Recommendation no.a Chinese TED guideline recommendations Survey concordance P
Endocrinologists Ophthalmologists
2 TED should be categorized based on its level of activity and severity. 85.36% 85.25% NS
3 The classification of TED activity period should be based on both CAS and imaging examinations. 49.09% 62.90% <0.05
4 It is recommended to establish a multidisciplinary approach for the diagnosis and treatment of TED 42.42% 29.03% <0.05
5 It is suggested to assess the effectiveness of treatment for TED by combining patient self-reporting (QOL) and objective measures reported by the doctor. 72.73% 47.58% <0.001
6 It is advised that TED patients quit smoking and control other risk factors. 63.48%b 33.86%b <0.001
10 Patients suffering from TED should undergo continuous ocular surface support therapy throughout the entire duration of their condition. 97.58% 100% NS
11 Intravenous glucocorticoids therapy is regarded as the primary treatment for patients with moderate, severe, and extremely severe cases of TED. 94.55% 95.16% NS
18 For patients who have been inactive or stable for at least 6 months, surgical treatment can be chosen. 28.48% 70.16% <0.001
21 In cases of TED complicated by DON, prompt initiation of high-dose intravenous glucocorticoid for 1–2 weeks is recommended. If there is no improvement, surgical intervention should be considered. 27.88% 61.29% <0.001

aRepresents the number in the Chinese guideline (13) on the diagnosis and treatment of thyroid-associated ophthalmopathy; bRepresents the percentage of respondents who took into account all the involved risk factors in the questionnaire at the same time.

TED, thyroid eye disease; CAS, clinical activity score; QOL, quality of life; DON, dysthyroid optic neuropathy.