Table 4.

Uni- and multivariate logistic regression analysis of factors influencing the risk of long-term hypothyroidism. Values are odds ratio with 95% CI. Values in bold indicate statistical significance.

	Univariate		Multivariate
	OR (95% CI)	P	OR (95% CI)	P
Gestational age	0.944 (0.877–1.017)	0.132	–
Pre-conception BMI	0.924 (0.841–1.016)	0.102	–
TSH (mU/L)	1.371 (1.083–1.736)	0.009	1.229 (0.952–1.585)	0.113
TPOAb ULN (continuous)	1.036 (0.969–1.107)	0.301	–
TPOAb positivity (categorical)	1.875 (0.810–4.340)	0.142	–
Maximal LT4 dose during pregnancy	1.040 (1.014–1.068)	0.003	1.031 (1.003–1.059)	0.030

LT4, levothyroxine; TPOAb ULN, a ratio of the absolute TPOAb value to the ULN; TPOAb, thyroperoxidase antibodies; ULN, upper normal limit.