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. 2013 Mar 28;2013(3):CD005028. doi: 10.1002/14651858.CD005028.pub3

Langner 2001 (P).

Methods DESIGN 
 Between‐patient
 Participant delivery
 ALLOCATION 
 Random
 Method of randomisation: unclear
 Concealment: unclear
 BLINDING 
 Double‐blind (participant/investigator)
 WITHDRAWAL/DROPOUT 
 Described 
Participants N: 44
Treatment duration: 6 wks; FU: 6 wks (14 wks for responders)
LF: 4 (9.1%)
BC: not reported
Age: not reported
Gender (per cent men): 54.5%
Severity: not reported
INCLUSION CRITERIA

  • Adults with chronic plaque psoriasis

  • BSA = 20%


EXCLUSION CRITERIA

  • Pregnancy

  • Inadequate contraception
Interventions

  • Calcitriol ointment 3 mcg/g BD (C)

  • Placebo ointment BD (P)
Outcomes

  1. IAGI (5‐pt: worse to clearance)
Notes The trial did not report sponsorship.
 All participants received 2 weeks' pre‐treatment with vehicle BD.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk The trial reported insufficient details.
Blinding (performance bias and detection bias) 
 All outcomes Low risk The trial was double‐blind (participant/investigator).
Randomisation method reported Unclear risk The trial did not report this.
Loss to follow up Low risk 9.1%
Baseline assessments Low risk These were partially done.
Baseline comparability demonstrated Unclear risk The trial did not report this.