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Development of P-tau217 cutoffs using site-specific training data. A ROC curve demonstrating diagnostic performance of P-tau217 in training data from Butler MAP cases/controls. B Histogram depicting the distribution of P-tau217 values (pg/mL) in Aβ negative (blue) and positive (red) participants, as well as Youden’s optimal cutoff (black dashed line) and the intermediate region (shaded gray). N = 50
