3. Design of a future study.

Methods	Allocation: randomised ‐ clearly described generation of sequence and concealment of allocation. Blinding: double ‐ described and tested. Duration: long term.
Participants	People with schizophrenia or schizophrenia‐like disorder. N = 500. Age: any. Sex: both. History: any.
Interventions	1. Trifluoperazine (oral). 2. Any low‐potency antipsychotic (oral).
Outcomes	Response (primary outcome) Rehospitalisation Mental state (BPRS) Global state (CGI) Leaving the study early (including specific causes) Death (natural and unnatural causes) Side‐effects Quality of life Satisfaction with care Employment

BPRS ‐ Brief Psychiatric Rating Scale
 CGI ‐ Clinical Global Impression