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. 2014 Dec 5;2014(12):CD009516. doi: 10.1002/14651858.CD009516.pub2

Comparison 1. Prophylactic intravenous antibiotics administered before cesarean incision versus after neonatal umbilical cord clamping (maternal outcomes).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Composite morbidity (as defined by trials) 10 5041 Risk Ratio (M‐H, Fixed, 95% CI) 0.57 [0.45, 0.72]
1.1 Cephalosporin 1 g 5 2144 Risk Ratio (M‐H, Fixed, 95% CI) 0.55 [0.35, 0.86]
1.2 Cephalosporin 2 g 5 2897 Risk Ratio (M‐H, Fixed, 95% CI) 0.57 [0.43, 0.76]
2 Endomyometritis 10 5041 Risk Ratio (M‐H, Fixed, 95% CI) 0.54 [0.36, 0.79]
2.1 Cephalosporin 1 g 5 2144 Risk Ratio (M‐H, Fixed, 95% CI) 0.58 [0.30, 1.12]
2.2 Cephalosporin 2 g 5 2897 Risk Ratio (M‐H, Fixed, 95% CI) 0.51 [0.32, 0.83]
3 Wound infection 10 5041 Risk Ratio (M‐H, Fixed, 95% CI) 0.59 [0.44, 0.81]
3.1 Cephalosporin 1 g 5 2144 Risk Ratio (M‐H, Fixed, 95% CI) 0.55 [0.30, 1.01]
3.2 Cephalosporin 2 g 5 2897 Risk Ratio (M‐H, Fixed, 95% CI) 0.61 [0.43, 0.88]
4 UTI/cystitis/pyelonephritis 8 4001 Risk Ratio (M‐H, Fixed, 95% CI) 1.02 [0.65, 1.59]
5 Pelvic abscess 1 741 Risk Ratio (M‐H, Fixed, 95% CI) 1.00 [0.06, 15.97]
6 Respiratory infection (pneumonia) 4 1849 Risk Ratio (M‐H, Fixed, 95% CI) 2.30 [0.34, 15.45]
7 Hospital length of stay (days) 2 1342 Mean Difference (IV, Fixed, 95% CI) ‐0.17 [‐0.30, ‐0.04]
8 Febrile Illness 4 2650 Risk Ratio (M‐H, Fixed, 95% CI) 0.93 [0.63, 1.35]