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. 2014 Dec 5;2014(12):CD009516. doi: 10.1002/14651858.CD009516.pub2

Comparison 2. Prophylactic intravenous antibiotics administered before cesarean incision versus after neonatal umbilical cord clamping (neonatal outcomes).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Sepsis 5 2907 Risk Ratio (M‐H, Fixed, 95% CI) 0.76 [0.51, 1.13]
2 Neonatal sepsis work up 4 1170 Risk Ratio (M‐H, Fixed, 95% CI) 0.92 [0.69, 1.23]
3 Infection with a resistant organism 1 379 Risk Ratio (M‐H, Fixed, 95% CI) 0.70 [0.12, 4.14]
4 Infection (other) 1 302 Risk Ratio (M‐H, Fixed, 95% CI) 0.93 [0.52, 1.64]
5 ICU admission 6 3708 Risk Ratio (M‐H, Fixed, 95% CI) 0.91 [0.74, 1.13]
6 ICU length of stay (days) 3 1731 Mean Difference (IV, Random, 95% CI) ‐0.07 [‐2.60, 2.46]
7 Neonatal antibiotic treatment 1 90 Risk Ratio (M‐H, Fixed, 95% CI) 0.84 [0.12, 5.68]
8 Fever 1 953 Risk Ratio (M‐H, Fixed, 95% CI) 0.67 [0.28, 1.62]