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. 2024 Jul 6;14:15583. doi: 10.1038/s41598-024-65887-4

Table 4.

The results of the GEE model for each cluster for men, women, and the overall population.

Gender Model Coefficient Cluster A Cluster B Cluster C Cluster D
Men 1 Intercept (SE) 4.137 (0.204)* 6.935 (0.632)* 8.831 (0.655)* 10.104 (1.367)*
Time (SE) 0.206 (0.041)* 1.462 (0.139)* 2.558 (0.181)* 4.255 (0.361)*
2 Intercept (SE) 1.947 (0.488)* 3.675 (1.142)* 2.122 (1.758) − 12.341 (7.530)
Time (SE) − 0.026 (0.039) 0.920 (0.172)* 1.714 (0.280)* 2.518 (0.560)*
Cardiovascular (SE) 0.649 (0.143)* 0.828 (0.232)* 0.834 (0.266)* 2.440 (0.745)*
Diabetes (SE) 0.102 (0.055) − 0.020 (0.118) 0.291 (0.316) 0.363 (0.407)
3 Intercept (SE) 0.476 (0.834) − 23.826 (6.617)* − 26.913 (5.098)* 59.894 85.673
Time (SE) − 0.089 (0.048) 0.727 (0.208)* 1.498 (0.242)* 4.099 (1.902)*
Cardiovascular (SE) 0.517 (0.177)* 0.642 (0.210)* 1.081 (0.177)* 1.807 (0.730)*
Diabetes (SE) 0.114 (0.084) − 0.081 (0.139) 0.294 (0.163) 0.237 (0.450)
HDI (SE) − 0.001 (0.025) 0.109 (0.077) − 0.370 (0.102)* − 0.338 (0.222)
LEB (SE) 0.041 (0.023) 0.315 (0.123)* 0.797 (0.137)* − 0.536 (1.116)
4 Intercept (SE) − 0.538 (0.916) − 20.122 (7.462)* − 5.223 (9.587) 154.006 (101.939)
Time (SE) − 0.042 (0.057) 0.383 (0.290) 1.499 (0.225)* 4.424 (1.860)*
Cardiovascular (SE) 0.475 (0.213)* 0.752 (0.206)* 1.022 (0.144)* 1.648 (0.777)*
Diabetes (SE) 0.068 (0.088) − 0.035 (0.158) 0.257 (0.167) 0.131 (0.528)
HDI (SE) 0.010 (0.025) 0.117 (0.103) − 0.353 (0.097)* − 0.160 (0.200)
LEB (SE) 0.037 (0.023) 0.316 (0.148)* 0.560 (0.169)* − 1.659 (1.295)
Alcohol (SE) 0.035 (0.027) − 0.034 (0.082) − 0.050 (0.071) − 1.103 (0.454)*
Tobacco (SE) 0.013 (0.010) − 0.087 (0.037)* − 0.109 (0.033)* − 0.116 (0.110)
Women 1 Intercept (SE) 6.067 (0.369)* 10.902 (1.186)* 18.696 (1.846)* 34.585 (3.418)*
Time (SE) 0.449 (0.062)* 2.836 (0.241)* 6.104 (0.437)* 7.304 (0.672)*
2 Intercept (SE) − 0.680 (0.752) 1.586 (1.736) 4.253 (4.580) − 13.471 (14.877)
Time (SE) 0.053 (0.061) 1.925 (0.290)* 5.300 (0.505)* 6.588 (0.616)*
Cardiovascular (SE) 2.100 (0.236)* 2.351 (0.383)* 1.800 (0.453)* 4.715 (1.314)*
Diabetes (SE) − 0.103 (0.080) − 0.446 (0.228) − 0.138 (0.739) − 0.184 (0.944)
3 Intercept (SE) − 3.248 (1.336)* − 1.506 (15.214) − 80.081 (30.989)* − 258.914 (120.852)*
Time (SE) − 0.111 (0.072) 1.900 (0.390)* 3.326 (0.655)* 4.123 (1.596)*
Cardiovascular (SE) 1.894 (0.261)* 1.511 (0.266)* 2.300 (0.525)* 5.260 (1.474)*
Diabetes (SE) − 0.123 (0.100) − 0.514 (0.208)* 1.277 (0.578)* 0.049 (0.650)
HDI (SE) 0.046 (0.026) 0.367 (0.136)* 0.049 (0.230) − 0.145 (0.311)
LEB (SE) 0.028 (0.026) − 0.220 (0.280) 0.943 (0.485) 3.179 (1.579)*
4 Intercept (SE) − 3.833 (1.497)* 17.721 (19.576) − 74.978 (32.041)* − 223.986 (117.016)
Time (SE) − 0.103 (0.081) 1.868 (0.562)* 3.032 (0.671)* 4.999 (1.257)*
Cardiovascular (SE) 2.035 (0.305)* 1.363 (0.362)* 2.470 (0.591)* 5.150 (1.621)*
Diabetes (SE) − 0.133 (0.102) − 0.347 (0.208) 1.271 (0.575)* 0.041 (0.735)
HDI (SE) 0.020 (0.027) 0.478 (0.197)* 0.110 (0.221) − 0.206 (0.313)
LEB (SE) 0.047 (0.027) − 0.550 (0.365) 0.859 (0.480) 2.725 (1.529)
Alcohol (SE) 0.206 (0.209) − 0.516 (0.630) − 0.413 (0.819) 0.261 (1.471)
Tobacco (SE) − 0.030 (0.017) 0.036 (0.066) − 0.096 (0.130) 0.156 (0.262)
Overall 1 Intercept (SE) 4.810 (0.226)* 7.737 (0.675)* 15.220 (1.17)* 33.027 (2.455)*
Time (SE) 0.330 (0.048)* 2.210 (0.182)* 4.206 (0.286)* 5.461 (0.545)*
2 Intercept (SE) − 2.473 (0.669)* − 5.514 (1.937)* − 1.777 (3.724) 1.408 (10.215)
Time (SE) 0.030 (0.034) 0.859 (0.258)* 2.742 (0.475)* 3.164 (0.892)*
Cardiovascular (SE) 1.916 (0.177)* 2.991 (0.423)* 2.248 (0.641)* 2.737 (0.922)*
Diabetes (SE) − 0.108 (0.066) − 0.451 (0.223)* 0.060 (0.770) 1.336 (1.131)
3 Intercept (SE) − 3.349 (1.007)* − 7.347 (7.708) − 39.068 (13.078)* − 37.305 (142.270)
Time (SE) − 0.030 (0.046) 1.142 (0.270)* 1.308 (0.473)* 1.589 (2.039)
Cardiovascular (SE) 1.807 (0.185)* 2.216 (0.268)* 2.426 (0.468)* 2.699 (0.804)*
Diabetes (SE) − 0.123 (0.069) − 0.643 (0.200)* 1.342 (0.324)* 1.711 (0.987)
HDI (SE) 0.025 (0.022) 0.229 (0.102)* − 0.045 (0.154) 0.789 (0.195)*
LEB (SE) 0.005 (0.019) − 0.130 (0.154) 0.511 (0.189)* − 0.330 (1.993)
4 Intercept (SE) − 2.139 (1.286) − 0.156 (8.922) − 25.963 (17.729) 11.201 (144.466)
Time (SE) − 0.023 (0.057) 0.973 (0.360)* 0.950 (0.512) 1.837 (1.574)
Cardiovascular (SE) 1.876 (0.217)* 2.345 (0.317)* 2.486 (0.511)* 2.639 (0.822)*
Diabetes (SE) − 0.126 (0.086) − 0.398 (0.227) 1.244 (0.372)* 1.480 (0.935)
HDI (SE) − 0.010 (0.024) 0.264 (0.101)* 0.038 (0.144) 0.843 (0.239)*
LEB (SE) 0.023 (0.020) − 0.247 (0.171) 0.368 (0.213) − 0.784 (2.018)
Alcohol (SE) − 0.005 (0.055) − 0.472 (0.139)* − 0.249 (0.242) − 1.619 (0.979)
Tobacco (SE) − 0.035 (0.014)* 0.027 (0.058) − 0.168 (0.123) 0.033 (0.179)

*Significant at 0.05 level.