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. Author manuscript; available in PMC: 2024 Jul 7.
Published in final edited form as: Annu Rev Pathol. 2023 Jan 24;18:515–535. doi: 10.1146/annurev-pathmechdis-031521-041424

Figure 5.

Figure 5

Morphologic variant forms of human papillomavirus (HPV)-associated oropharyngeal carcinoma include those that take on highly developed basaloid (a), lymphoepithelial (b), and ciliated (c) features. The presence of a high-grade neuroendocrine component (d) is a finding that signals aggressive tumor behavior.