Table 8.
Clinical signs and symptoms, and adverse events after treatment with chloroquine plus primaquine
| Adverse events and clinical sign and symptoms | Follow up days | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Day 0 | Day 1 | Day 2 | Day3 | Day 7 | Day 14 | Day 21 | Day 28 | Day 35 | Day 42 | |
| Fever (%) | 100 | 5 | 1 | 2 | 1 | 3 | 2 | 0 | 2 | 1 |
| Chills (%) | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| Headache (%) | 94 | 3 | 2 | 5 | 2 | 4 | 2 | 2 | 1 | 1 |
| Nausea n (%) | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Vomiting (%) | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cough (%) | 3 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Joint pain (%) | 40 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Mouse ulcer (%) | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
| Dark urine (%) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
*Urine colour grade using Hillmen urine colour chart, all participants were recorded < 5