Fig. 2.

Effect of ENT-A011 on mouse astrocytes. The compound induces TrkB and its downstream target Akt phosphorylation after 20 min treatment in astrocytes. Representative blots (A) and quantification (A′) of 4 independent experiments are shown. Error bars represent S.E.M., Student’s t-test against Control; *p < 0.05; ***p < 0.001. B ENT-A011 increases Bdnf, Wnt, Creb and TrkB expression (detected by RT-qPCR) after LPS treatment in astrocytes. N = 3–4, error bars represent S.E.M., Student’s t-test against Control; *p < 0.05, **p < 0.01