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Cryo-EM structure of mTORC1. Color coded ribbon representation of mTORC1 structure showing the three essential components of human mTORC1. Serine/threonine-protein kinase mTOR (Red/Green), Regulatory-associated protein of mTOR RPTOR (yellow/black), and Target of rapamycin complex subunit LST8 (blue/celeste) are combined into a symmetric dimer of an heterotrimer consisting of mTOR, Raptor, and mLST8 itself. Adapted from Yang et al. (2016).
