Table 1.
Characteristics of patient cohort.
| Demographics * | Study arm | ||||
| Control | 45 | 52% | |||
| Intervention | 42 | 48% | |||
| Sex | |||||
| Female | 43 | 49% | |||
| Male | 44 | 51% | |||
| Race | |||||
| White/Caucasian | 56 | 65% | |||
| Black | 9 | 10% | |||
| Asian | 7 | 8% | |||
| More than 1 race identified | 2 | 2% | |||
| Other/Unknown | 13 | 15% | |||
| Antenatal Steroids (yes, %) | 78 | 90% | |||
| Gestational age at birth, wk | 27.2 | 2.5 | |||
| Hormone Levels | IGF-1 level (ng/mL) | ||||
| DOL 7 | 75 | 86% | 26.1 | 9.6 | |
| 35 weeks PMA | 62 | 71% | 40.2 | 14.7 | |
| IGFBP-3 level (mcg/mL) | |||||
| DOL 7 | 77 | 89% | 0.9 | 0.3 | |
| 35 weeks PMA | 66 | 76% | 1.3 | 0.4 | |
| Birth weight, length, OFC * | Birth weight, grams (z-score) | 87 | 942.9 (−0.2) | 285.4 (0.8) | |
| Birth length, cm (z-score) | 87 | 34.5 (−0.2) | 4.2 (1) | ||
| Birth OFC, cm (z-score) | 87 | 24 (−0.5) | 3.3 (1.6) | ||
| NICU Nutritional Intake * | First week of life nutrition | 87 | |||
| Kilocalorie intake/kg | 95.9 | 15.8 | |||
| Protein intake/kg | 4.2 | 0.4 | |||
| Kilocalories/kg from enteral feeds | 22.8 | 18.7 | |||
| Protein g/kg from enteral feeds | 0.7 | 0.7 | |||
| NICU Comorbidities | SNAP-II score, day 1–2 | 87 | 25 | 23.5 | |
| Hyperglycemia >180 mg/dL (# episodes) | 87 | 1.7 | 2.4 | ||
| Insulin treatment (# days) | 87 | 1.1 | 2.4 | ||
| Hypertriglyceridemia >300 mL/dL (# episodes) | 87 | 0.3 | 0.6 | ||
| Hypoglycemia <40 mg/dL (# episodes) | 87 | 0 | 0.2 | ||
| IVH, none/grade 1 | 73 | 84% | |||
| IVH, ≥grade 2 | 14 | 16% |
PMA Postmenstrual age, DOL Day of life, SD Standard deviation, OFC Occipital-frontal circumference, SNAP-II Score for Neonatal Acute Physiology, IVH Intraventricular hemorrhage.
*
Portions of this data has been previously published.