Table 1.

Types of Sialidases.

Categorization	Position	Substrate	Function	References
NEU1	Lysosome	Oligosaccharide, glycopeptides	Phagocytosis, lysosomal degradation, cytotoxicity, immunity	(42–44)
NEU2	Cytoplasm	Oligosaccharide, glycoprotein, gangliosides	Differentiation of myoblasts and neural cells	(42, 45, 46)
NEU3	Cytoplasmic membrane	Gangliosides	Differentiation, apoptosis, and adhesion of neural cells	(47–49)
NEU4	Endoplasmic reticulum, lysosomes, mitochondria	Oligosaccharide, glycoprotein, gangliosides	Differentiation, apoptosis, and adhesion of neural cells	(42, 50, 51)