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. 2024 Jun 24;16:1399285. doi: 10.3389/fnagi.2024.1399285

Table 1.

Demographic and clinical features of patients with Parkinson’s disease among different H&Y stages (PD) (n = 243).

Variables [Mean ± SD or n (%)] H&Y stage I H&Y stage II H&Y stage III
n (%) 87 (35.80%) 80 (32.92%) 76 (31.27%)
Age (yrs.) 66.26 ± 6.17 70.56 ± 6.14 71.53 ± 6.33
Female 37 57 38
50 23 38
BMI 23.84 ± 3 23.16 ± 2.6 23.71 ± 3.09
MDS-UPDRS Part III 13.75 ± 5.46 24.74 ± 7.39 29.5 ± 9.49
Balance and Risk of Fall
BBS 51.47 ± 3.19 46.23 ± 3.86 38.39 ± 7.29
TUG (seconds) 11.44 ± 18.4 13.09 ± 4.75 20.97 ± 20.61
FTSST (seconds) 11.35 ± 2.79 14.05 ± 4.71 17.25 ± 8.12
Muscle strength outcomes
Knee flexion (N·m) 24.86 ± 12.31 18.92 ± 9.14 13.51 ± 7.51
Knee extension (N·m) 50.68 ± 22.36 41.18 ± 19.54 29.14 ± 15.95
Gait cycle assessment
FOG 4.25 ± 4.32 7.21 ± 5.79 9.72 ± 6.97
Step length(m) 0.51 ± 0.07 0.45 ± 0.09 0.38 ± 0.1
Speed of gait(m/s) 0.96 ± 0.18 0.82 ± 0.17 0.67 ± 0.2
Toe-off angle (°) 30.97 ± 11.57 24.09 ± 10.82 21.07 ± 8.64
Quality of life
Mobility 12.16 ± 15.31 26.53 ± 18.78 39.08 ± 26.43
Activities of daily living 10.35 ± 11.57 23.39 ± 20.59 28.34 ± 25.76
Emotional well-being 17.67 ± 17.07 24.9 ± 20.97 16.89 ± 19.85
Stigma 19.83 ± 22.52 28.59 ± 28.05 22.53 ± 23.39
Social support 8.81 ± 14.84 14.27 ± 18 11.4 ± 17.52
Cognition 24.07 ± 16.33 27.97 ± 18.28 29.03 ± 21.3
Communication 8.14 ± 14.49 16.87 ± 19.12 27.3 ± 28.01
Bodily discomfort 28.83 ± 20.95 31.77 ± 21.95 37.94 ± 25.76
PDQ-39 SI 16.23 ± 10.77 24.29 ± 13.34 26.56 ± 15.51

BMI, body mass index; H&Y, Hoehn and Yahr; MDS-UPDRS, movement disorder society–sponsored revision of the Unified Parkinson’s Disease Rating Scale; BBS, Berg Balance Scale; TUG, timed up-to-go test; FTSST, five times sit-to-stand test; FOG, freezing of gait; PDQ-39 SI, the 39-item Parkinson’s disease questionnaire summary index score.