Table 3.

Associations between systemic inflammation indicators and NAFLD.

variables	Model 1	Model 2	Model 3
C-reactive protein (mg/L)
<1.0	1.00 (ref.)	1.00 (ref.)	1.00 (ref.)
(1.0, 2.0)	1.52 (1.38~1.67)	1.32 (1.20~1.45)	1.30 (1.18~1.43)
(2.0, 3.0)	2.09 (1.88~2.32)	1.66 (1.49~1.85)	1.61 (1.44~1.79)
(3.0, 4.0)	2.47 (2.20~2.78)	1.85 (1.64~2.09)	1.77 (1.57~2.00)
>=4.0	3.17 (2.84~3.54)	2.29 (2.05~2.57)	2.18 (1.95~2.45)
Lymphocyte count (10^9cells/L)
<1.0	1.09 (1.01~1.18)	1.10 (1.01~1.19)	1.10 (1.02~1.19)
(1.0, 2.0)	1.00 (ref.)	1.00 (ref.)	1.00 (ref.)
(2.0, 3.0)	1.10 (1.01~1.19)	1.05 (0.96~1.14)	1.03 (0.95~1.12)
(3.0, 4.0)	1.24 (1.11~1.38)	1.11 (0.99~1.26)	1.08 (0.97~1.20)
>=4.0	1.44 (1.25~1.65)	1.15 (0.99~1.32)	1.09 (0.94~1.25)
Monocyte count (10^9cells/L)
<0.3	1.00 (ref.)	1.00 (ref.)	1.00 (ref.)
(0.3, 0.5)	1.11 (1.02~1.21)	1.05 (0.96~1.14)	1.04 (0.95~1.13)
(0.5, 0.7)	1.25 (1.14~1.36)	1.10 (1.01~1.20)	1.08 (0.99~1.18)
(0.7, 0.9)	1.41 (1.27~1.57)	1.17 (1.05~1.30)	1.13 (1.02~1.26)
>=0.9	1.96 (1.77~2.17)	1.47 (1.32~1.63)	1.40 (1.26~1.56)
Neutrophil count (10^9cells/L)
<2.0	1.00 (ref.)	1.00 (ref.)	1.00 (ref.)
(2.0, 4.0)	1.19 (1.08~1.31)	1.12 (1.02~1.23)	1.09 (0.99~1.20)
(4.0, 6.0)	1.36 (1.24~1.50)	1.22 (1.10~1.34)	1.16 (1.06~1.28)
(6.0, 8.0)	1.58 (1.42~1.77)	1.34 (1.20~1.50)	1.26 (1.13~1.41)
>=8.0	1.86 (1.65~2.09)	1.47 (1.30~1.66)	1.35 (1.20~1.53)
Lymphocyte-to-monocyte ratio (LMR)
<3.0	1.00 (ref.)	1.00 (ref.)	1.00 (ref.)
(3.0, 4.0)	0.75 (0.69~0.82)	0.80 (0.74~0.88)	0.81 (0.74~0.88)
(4.0, 5.0)	0.69 (0.63~0.76)	0.77 (0.70~0.84)	0.77 (0.70~0.85)
(5.0, 6.0)	0.69 (0.62~0.76)	0.77 (0.70~0.86)	0.78 (0.70~0.87)
>=6.0	0.69 (0.63~0.77)	0.77 (0.69~0.86)	0.77 (0.70~0.86)
Neutrophil-to-lymphocyte ratio (NLR)
<2.0	1.00 (ref.)	1.00 (ref.)	1.00 (ref.)
(2.0, 3.0)	0.91 (0.82~1.01)	0.91 (0.83~1.01)	0.91 (0.8~1.00)
(3.0, 4.0)	0.95 (0.86~1.05)	0.94 (0.85~1.04)	0.93 (0.84~1.02)
(4.0, 5.0)	1.15 (1.03~1.28)	1.12 (1.01~1.25)	1.10 (0.99~1.22)
>=5.0	1.29 (1.17~1.42)	1.21 (1.10~1.34)	1.18 (1.07~1.30)
Platelet-to-lymphocyte ratio (PLR)
<100	1.45 (1.32~1.59)	1.24 (1.13~1.36)	1.21 (1.18~1.33)
(100, 120)	1.19 (1.08~1.31)	1.10 (1.00~1.22)	1.10 (1.00~1.21)
(120, 150)	1.07 (0.98~1.17)	1.03 (0.94~1.13)	1.03 (0.94~1.12)
(150, 200)	1.00 (ref.)	1.00 (ref.)	1.00 (ref.)
>=200	1.14 (1.03~1.27)	1.16 (1.04~1.28)	1.15 (1.04~1.28)
Systemic immune-inflammation index (SII)
<400	1.00 (ref.)	1.00 (ref.)	1.00 (ref.)
(400, 500)	0.92 (0.84~1.02)	0.93 (0.85~1.02)	0.92 (0.84~1.01)
(500, 600)	0.98 (0.89~1.08)	0.98 (0.89~1.08)	0.97 (0.88~1.07)
(600, 800)	0.97 (0.90~1.08)	0.98 (0.90~1.08)	0.96 (0.88~1.05)
>=800	1.19 (1.09~1.30)	1.16 (1.06~1.27)	1.12 (1.05~1.22)

Values were presented as hazard ratios (95% confidence interval).