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. 2023 Apr 18;77(7):478–485. doi: 10.1136/jcp-2023-208852

Table 4.

Schematic representation of HRD score evaluated by each participating institution by using commercially available NGS assays on a retrospective series of diagnostic HGSOC specimens

Sample ID Centre #1 Centre #2 Centre #3
Illumina NextSeq 550Dx Illumina HiSeq 2500 Ion Gene Studio S5 Plus System Illumina NextSeq 550 platform
SOPHiA DDM HRD solution panel MyChoice CDx Myriad HRD Oncomine HRR pathway panel Amoy HRD focus panel
ID_1 POS NEG POS* POS
ID_2 POS POS NEG POS
ID_3 POS POS POS POS
ID_4 NEG POS POS POS
ID_5 NEG NEG NEG NEG
ID_6 NEG NEG NEG NEG
ID_7 NEG NEG NEG NEG
ID_8 NEG NEG NEG NEG
ID_9 NEG NEG NEG NEG
ID_10 NEG NEG NEG NA
ID_11 POS POS NEG NA
ID_12 NEG NEG NEG NEG
ID_13 POS POS NEG POS
ID_14 NEG NEG NEG NEG
ID_15 NEG NEG NEG NEG
ID_16 POS POS POS POS
ID_17 NEG NEG NEG POS*
ID_18 NEG NEG NEG NA
ID_19 POS POS POS POS
ID_20 NEG NEG NEG NEG

*Borderline results.

HRD, homologous recombination deficiency; HRR, homologous recombination repair; ID, identify number; NA, not assessed; NEG, negative; NGS, next-generation sequencing; POS, positive.