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. 2024 Jun 7;16(6):e61898. doi: 10.7759/cureus.61898

Table 1. Diagnostic criteria for TN set forth by major specialty societies.

Specialty societies have defined diagnostic criteria for TN [3,7,12-14]

MS: multiple sclerosis; TN: trigeminal neuralgia

Characteristic Third edition of International Classification of Headache Disorders International Association for the Study of Pain European Academy of Neurology
Triggers Innocuous stimuli along the trigeminal distribution Innocuous stimuli along the trigeminal distribution, but pain may arise spontaneously Not mentioned
Pain Paroxysms with or without concomitant underlying pain Paroxysmal pain but concomitant underlying pain is possible May be purely paroxysmal or paroxysmal plus concomitant persistent pain
Painful paroxysms Lasts from less than one second to two minutes. Severe intensity. Often has an “electric” or stabbing quality Few seconds to a maximum of two minutes. Severe intensity Painful paroxysms
Location Along distributions of trigeminal nerve, typically unilateral Along distributions of the trigeminal nerve, typically unilateral. TN secondary to MS is sometimes bilateral Along distributions of trigeminal nerve, usually unilateral, but younger and secondary patients may have bilateral symptoms
Trigeminal sensory deficits Not mentioned Not mentioned More common in those with secondary TN than primary