Table 6. Smaller studies have established associations between trigeminal neuralgia and other conditions.

Conditions appear in alphabetical order [30-34]

Condition	Study	Conclusions
Anxiety and depression	Mendelian randomization database analysis	These conditions significantly increased the risk of trigeminal neuralgia. However, years of education emerged as a protective factor against trigeminal neuralgia in this population
Autoimmune disorders
Dementia	Case-matched study	Dementia incidence was 4.47-fold greater in trigeminal neuralgia patients than in controls and was a greater risk in younger trigeminal neuralgia patients than older ones
Diabetes mellitus	Case-matched study	21.9% of trigeminal neuralgia had diabetes versus 12.9% of controls (p = 0.01)
Osteoporosis	Case-matched study, 14 years	Osteoporosis patients had 0.60 cases of trigeminal neuralgia per 1000 person-years compared to 0.18 per 1000 for controls