Table 3.
Effects of sex, diabetes status, and operation choice on percentage total weight loss at postoperative years 1, 2, and 5, stratified by sex*
| Female patients | Male patients | |||||
|---|---|---|---|---|---|---|
| Mean weight loss % (95% CI) | Adjusted difference % (95% CI) | P value for difference | Mean weight loss % (95% CI) | Adjusted difference % (95% CI) | P value for difference | |
| Year 1 | ||||||
| No diabetes | 33.3 (33.1, 33.4) | Ref. | 32.7 (32.4, 33.1) | Ref. | ||
| Diabetes | 30.6 (30.4, 30.8) | −2.83 (−3.14, −2.51) | <.0001 | 28.5 (28.2, 28.8) | −3.47 (−4.10, −2.83) | <.0001 |
| RYGB | 33.5 (33.4, 33.7) | Ref. | 31.3 (31.0, 31.6) | Ref. | ||
| VSG | 28.6 (28.3, 28.8) | −5.14 (−5.47, −4.80) | <.0001 | 27.9 (27.4, 28.5) | −4.31 (−4.99, −3.64) | <.0001 |
| Year 2 | ||||||
| No diabetes | 34.1 (33.9, 34.4) | Ref. | 33.2 (32.6, 33.8) | Ref. | ||
| Diabetes | 30.4 (30.1, 30.7) | −3.75 (−4.08, −3.43) | <.0001 | 29.3 (28.8, 29.9) | −3.39 (−4.07, −2.72) | <.0001 |
| RYGB | 34.4 (34.2, 34.6) | Ref. | 31.7 (31.3, 32.1) | Ref. | ||
| VSG | 27.3 (26.9, 27.7) | −7.43 (−7.79, −7.08) | <.0001 | 28.3 (27.4, 29.1) | −3.40 (−4.11, −2.68) | <.0001 |
| Year 5 | ||||||
| No diabetes | 28.9 (28.4, 29.3) | Ref. | 30.2 (28.9, 31.5) | Ref. | ||
| Diabetes | 25.8 (25.3, 26.2) | −2.91 (−3.30, −2.51) | <.0001 | 22.3 (21.5, 23.1) | −2.43 (−3.28, −1.59) | <.0001 |
| RYGB | 28.7 (28.4, 29.1) | Ref. | 25.0 (24.3, 25.7) | Ref. | ||
| VSG | 21.6 (20.9, 22.3) | −8.00 (−8.46, −7.54) | <.0001 | 22.9 (21.0, 24.8) | −2.88 (−3.79, −1.98) | <.0001 |
Ref. = reference; RYGB = Roux-en-Y gastric bypass; VSG = vertical sleeve gastrectomy.
*
Generalized linear mixed models adjusted for age (years), preoperative body weight (kilograms), race (Black versus White), diabetes status (diabetes versus no diabetes), procedure (VSG versus RYGB), time (months, modeled using a spline function with knots at 0, 12, 24, 36, and 63 mo), and interactions between time spline and the aforementioned variables.