Fig. 6.

Diagnostic value of the miR-200 family signature, which improved by addition of CA 19 − 9. Receiver operating characteristic curves and corresponding area under the curve values (AUCs) for (A) the miR-200 family (PDAC n = 30 vs. benign disease n = 31), (B) CA 19 − 9 (PDAC n = 28 vs. benign disease n = 14) and (C) the combination of the miR-200 family and CA 19 − 9 (PDAC n = 28 vs. benign disease n = 14). Patients with missing values for CA19-9 were not included in the analyses of (B) and (C). *p < 0.05, **p < 0.005, ***p < 0.0005, ****p < 0.0001