TABLE 1.
Infection of primary primate fibroblasts by cell-free murine leukemia virus core-PERV env pseudotype particles
| Cell type | PERV pseudotypea:
|
Control
|
||
|---|---|---|---|---|
| envA | envB | envC | MLVb A | |
| Human foreskin fibroblast | + | − | − | + |
| Human MRC5 fetal fibroblast | + | − | − | + |
| Pan troglodytes PTR | + | − | − | + |
| Gorilla gorilla GGO205 | + | − | − | + |
| Papio hamadryas 312 | + | − | − | + |
| Papio hamadryas 419 | + | − | − | + |
| Papio hamadryas 420 | + | − | − | + |
| Papio hamadryas 421 | + | − | − | + |
| Papio hamadryas 423 | + | − | − | + |
| Papio papio 373 | (+) | ? | − | + |
| Macacca nemestrina | − | − | − | + |
| Macacca fascicularis 383 | − | − | − | + |
| Macacca nigra 381 | − | − | − | + |
| Macacca nigra 382 | − | − | − | + |
| Cercopithecus aethiops CAE27 | − | − | − | + |
| Cercopithecus aethiops CAEB | − | − | − | + |
| Pygathrix nemaeus PNE | − | − | − | + |
| Colobus guerezza CGU | − | − | − | + |
| Saimiri boliviensis 374 | − | − | − | + |
| Alouatta seniculus ASE | − | − | − | + |
| Controls | ||||
| HEK293 | + | + | − | + |
| ST-IOWA | + | + | + | − |
a
Results of pseudotype assays are depicted. The symbol (+) means that the results could not be reproduced in all of the experiments. envB infection in P. papio could not be clearly interpreted due to very high β-galactosidase background staining. Murine leukemia virus A was the amphotropic positive control. Infection experiments were reproduced at least three times.
b
MLV, murine leukemia virus.