Table 3.
Mediation Analysis Using Overall and Theme-Specific Census Tract SVI Rankings
| SVI Measure | Natural Indirect Effect HR (95% CI)a | Natural Direct Effect HR (95% CI)b | Proportion Mediated |
|---|---|---|---|
| Overall SVI rankings | 1.28 (1.07-1.72) | 1.07 (0.76-1.38) | 0.81 |
| Theme-specific rankings | |||
| Socioeconomic status | 1.35 (1.10-1.74) | 1.01 (0.75-1.25) | 0.98 |
| Household composition and disability | 1.13 (0.99-1.29) | 1.21 (0.97-1.50) | 0.42 |
| Minority status and language | 1.03 (0.85-1.25) | 1.33 (1.05-1.77) | 0.11 |
| Housing type and Transportation | 1.02 (0.94-1.14) | 1.32 (1.07-1.63) | 0.09 |
Details of the specific methods used in the mediation analysis are provided in the Supplemental Methods.
SVI = social vulnerability index.
a
Represents the association between Black race and the time to major adverse cardiovascular event that is mediated by the SVI variable under consideration.
b
Represents the association between Black race and the time to major adverse cardiovascular event through other pathways not related to the SVI theme under consideration.