Figure 3.
Elbow angles for Fabs D08 (a), D08* (b), BLV5B8 (c) and BLV5B8* (d) presented in cartoon representation. Chains are coloured as in Fig. 1 ▸: the BLV5B8 HC is in white, the D08 HC is in black, the BLV5B8 LC is in magenta and the D08 LC is in red. Blue dumbbells indicate psuedo-dyad rotation axes of each immunoglobulin domain with calculated hinge residues highlighted as green spheres (LC) or red spheres (HC). Elbow angles (Stanfield et al., 2006 ▸) were visualized using the PyMOL Elbow Angle script (Sampson, 2014 ▸).