Table 1.
Descriptive analysis of demographic characteristics of the patients and tumor characteristics
| n (%) | ||
|---|---|---|
| Age (years) | Min-max (median) | 1–71 (44) |
| Mean±SD | 41.96±21.88 | |
| Sex | Female | 10 (40.0) |
| Male | 15 (60.0) | |
| Diagnosis | Osteosarcoma | 9 (36.0) |
| Ewing sarcoma | 3 (9.0) | |
| Pleomorphic sarcoma | 3 (9.0) | |
| Chondrosarcoma | 2 (8.0) | |
| Fibrosarcoma | 2 (8.0) | |
| Dermatofibrosarcoma protuberans | 1 (4.0) | |
| Leimyosarcoma | 1 (4.0) | |
| Myofibroblastic sarcoma | 1 (4.0) | |
| Myxofibrosarcoma | 1 (4.0) | |
| Rabdomyosarcoma | 1 (4.0) | |
| Synovial Sarcoma | 1 (4.0) | |
| Tumor localization | Upper extremity | 6 (24.0) |
| Lower extremity | 19 (76.0) | |
| Tumor depth | Superficial | 0 (0.0) |
| Deep | 25 (100.0) | |
| Tumor size (cm) | Min-max (median) | 4–30 (9) |
| Mean±SD | 10.20±5.45 | |
| Tumor grade | Grade 1 | 4 (16.0) |
| Grade 2 | 3 (12.0) | |
| Grade 3 | 18 (72.0) | |
| Surgical margin | Wide | 16 (64.0) |
| Marginal | 5 (20.0) | |
| Intralesional | 4 (16.0) | |
| Closure of wound | Primary | 18 (72.0) |
| STSG | 3 (12.0) | |
| Free flap | 4 (16.0) | |
| Indications of amputation | Oncological indications | |
| Local recurrence | 18 (72.0) | |
| Non-oncological indications | ||
| Prosthetic infection | 5 (20.0) | |
| Mechanic failure | 1 (4.0) | |
| Skin necrosis | 1 (4.0) | |
| Number of operations before amputation | Min-max (median) | 1–4 (2) |
| Mean±SD | 2±0.76 | |
| Amputation decision for oncological indications | 1st local recurrence | 4 (22.2) |
| 2nd local recurrence | 11 (61.1) | |
| >2nd local recurrence | 3 (16.7) | |
| Metastasis before amputation | Yes | 13 (52.0) |
| No | 12(48.0) | |
| Metastasis at follow-up | Yes | 22 (88.0) |
| No | 3 (12.0) | |
| Survival status | Alive | 11 (44.0) |
| Dead | 14 (56.0) | |
| Follow-up (month) | Min-max (median) | 6–125 (27) |
| Mean±SD | 39.88±31.59 |
SD: standard deviation; STSG: split thickness skin graft.