Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Jul 7;16(1):2374608. doi: 10.1080/19490976.2024.2374608

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2024 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

PMC Copyright notice

Figure 4. — QA altered gut microbe-associated metabolites.

(a) PLS-DA of fecal metabolic profile. (b) Volcano map of significantly up- and down-regulated metabolites between HFD and HFD+QA group. (c) Wayne diagram. (d) KEGG pathway classification of metabolites. (e) Heatmap of differential tryptophan metabolites. (f) Correlation heatmap of tryptophan metabolites with oxidative stress indicators, inflammatory cytokines and AD indicators. (g) Ecological network among differential tryptophan metabolites with oxidative stress indicators, inflammatory cytokines and AD indicators. (h) ROC analysis of IAA and KYNA. (i) The abundance of IAA and KYNA in different groups. *p < .05, **p,< .01, ***p < .001. PLS-DA, Partial Least Squares Discrimination Analysis; ROC, Receiver Operating Characteristic; IAA, Indole-3-acetic acid; KYNA, Kynurenic acid.