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. 2024 Jun 15;15(6):1091–1110. doi: 10.4239/wjd.v15.i6.1091

Figure 1.

Figure 1

Clinical and pathologic characteristics of obesity-related kidney injures. HSFD: High-sucrose and high-fat diet; HFD: High-fat diet; ORN: Obesity-related nephropathy; ORG: Obesity-related glomerulopathy; ESRD: End-stage renal disease; FSGS: Focal segmental glomerulosclerosis; IgA: Immunoglobulin A; DN: Diabetic nephropathy; ABCA1: ATP-binding cassette transporter; ADRP: Adipocyte differentiation-related protein; SREBP-1: Sterol response element binding protein-1; TGF-β: Transforming growth factor-β; NEFAs: Non-esterified fatty acids; TNF-α: Tumor necrosis factor-α; IL-6: Interleukin-6; MCP-1: Moncyte chemoattractant protein-1; IL-β: Interleukin-β; IGF-1: Insulin growth factor-1; NF-κB: Nuclear factor-kappa B; FFAs: Free fatty acids; AMPK: Adenosine 5-monophosphate activated protein kinase.