Table 2.
Comparison of preoperative and postoperative serum indices between the two subgroups, mean ± SD
|
Index
|
Time
|
EUS-BD (n = 33)
|
PTBD (n = 35)
|
t
|
P value
|
| TP (g/L) | Before surgery | 61.85 ± 7.14 | 59.25 ± 7.12 | -1.498 | 0.139 |
| 7 d after surgery | 41.75 ± 5.80a,b | 55.13±6.82a | 8.687 | < 0.001 | |
| ALB (g/L) | Before surgery | 44.04 ± 6.98 | 40.97 ± 6.70 | -1.846 | 0.069 |
| 7 d after surgery | 31.20 ± 4.45a,b | 39.55 ± 6.07a | 6.439 | < 0.001 | |
| ALP (U/L) | Before surgery | 529.68 ± 182.52 | 505.45 ± 176.87 | -0.559 | 0.578 |
| 7 d after surgery | 285.39 ± 97.22a,b | 360.65 ± 150.02a | 2.439 | 0.017 | |
| ALT (U/L) | Before surgery | 148.76 ± 52.55 | 146.58 ± 53.35 | -0.169 | 0.866 |
| 7 d after surgery | 51.33 ± 6.61a,b | 73.58 ± 7.03a | 13.424 | < 0.001 | |
| AST (U/L) | Before surgery | 121.29 ± 37.58 | 107.62 ± 28.98 | -1.685 | 0.097 |
| 7 d after surgery | 42.02 ± 13.95a,b | 75.03 ± 16.25a | 8.969 | < 0.001 | |
| GGT (U/L) | Before surgery | 612.05 ± 179.24 | 575.13 ± 174.30 | -0.861 | 0.391 |
| 7 d after surgery | 213.67 ± 61.37a,b | 299.65 ± 65.12a | 5.595 | < 0.001 | |
| TBIL (mmol/L) | Before surgery | 228.02 ± 66.39 | 205.23 ± 76.28 | -1.311 | 0.194 |
| 7 d after surgery | 107.93 ± 52.43a,b | 144.79 ± 59.10a | 2.714 | 0.008 | |
| DBIL (mmol/L) | Before surgery | 204.18 ± 52.86 | 192.13 ± 49.66 | -0.969 | 0.336 |
| 7 d after surgery | 70.19 ± 17.16a,b | 84.48 ± 19.41a | 3.208 | 0.002 | |
| TBA (mmol/L) | Before surgery | 228.62 ± 55.45 | 208.90 ± 63.35 | -1.362 | 0.178 |
| 7 d after surgery | 66.31 ± 18.61a,b | 90.55 ± 20.11a | 5.152 | < 0.001 | |
| hs-CRP (mg/L) | Before surgery | 13.22 ± 3.29 | 11.60 ± 3.90 | -1.843 | 0.070 |
| 7 d after surgery | 4.58 ± 1.33a,b | 7.66 ± 2.36a | 6.576 | < 0.001 |
a
P < 0.05, compared to the preoperative subgroup.
b
P < 0.05 compared to the percutaneous transhepatic puncture biliary drainage subgroup.
TP: Total protein; ALB: Albumin; ALP: Serum alkaline phosphatase; ALT: Alanine aminotransferase; AST: Aspartate transaminase; GGT: Gamma-glutamyl transferase; TBIL: Total bilirubin; DBIL: Direct bilirubin; TBA: Total bile acid; hs-CRP: Hypersensitive C-reactive protein; EUS-BD: Endoscopic ultrasound-guided biliary drainage; PTBD: Percutaneous transhepatic puncture biliary drainage.