Figure 1. β-glucan significantly reduces OvCa fluid tumor burden.

(A) Representative bioluminescence images and quantification of bioluminescence signals in PBS- and β-glucan-treated ID8 tumor-bearing mice 42 days post tumor-seeding. (B) Representative pictures of peritoneal lavage and (C) quantification of GFP⁺ ID8 OvCa cells in the peritoneal lavage of PBS- and β-glucan-treated mice. (D) Tissue of origin and mutation status of Trp53, Kras, Ccne1, and Akt2 in ID8 and KPCA OvCa cell lines. (E) Quantification of KPCA cells in the peritoneal lavage one week after KPCA seeding. (F) quantification of omentum bioluminescence signals one week after KPCA seeding. (G) Representative bioluminescence images and quantification of bioluminescence signals in PBS- and β-glucan-treated KPCA tumor-bearing mice. (H) Representative pictures of peritoneal lavage and (I) quantification of GFP⁺ KPCA OvCa cells in the peritoneal lavage in PBS- and β-glucan-treated mice. Student’s t test was used *p<0.05 ; ****p<0.0001. Error bars are standard errors of the mean.