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[Preprint]. 2024 Jun 27:rs.3.rs-4559587. [Version 1] doi: 10.21203/rs.3.rs-4559587/v1

Table 3.

Crude Associations Between Clinical and Psychosocial Factors and AET Adherence Ratio

Factor β-coefficient Standard Error p-value1
Clinical
Comorbid HIV Infection −0.03 0.03 0.31
Age 0.01 0.01 0.29
BC Stage (I/II vs III) −0.01 0.03 0.64
HER2 Status (Positive vs Negative) 0.01 0.03 0.91
Tamoxifen Prescription 0.02 0.03 0.61
Number of Other Medications Used (Non-ART) −0.01 0.01 0.42
Social
Married/Domestic Partner 0.02 0.02 0.28
Tobacco Smoking 0.06 0.05 0.21
Alcohol Use 0.02 0.02 0.57
Wealth Percentile 0.02 0.01 0.06
Psychosocial
SSSS - Partner 0.001 0.01 0.69
SSSS - Women in Your Family 0.002 0.01 0.63
SSSS - Friends 0.01 0.004 0.09
SSSS - HCP 0.002 0.01 0.70
HELT-LL - Total Score 0.003 0.003 0.32
BMQ - AET Concerns −0.01 0.003 0.001
BMQ - AET Necessity −0.003 0.004 0.40
BMQ - General Overuse −0.01 0.003 0.11
BMQ - General Harms −0.01 0.004 0.16
CASE-Cancer - Total Score 0.003 0.003 0.45
CES-D Score −0.002 0.001 0.12
GAD-7 Score −0.01 0.002 0.04
PSS Score −0.002 0.002 0.29
AET-Related Side Effects
Cognitive −0.001 0.001 0.91
Musculoskeletal −0.001 0.001 0.88
Vasomotor −0.01 0.003 0.07
Gastrointestinal −0.02 0.01 0.09
Dyspareunia 0.001 0.007 0.87
Weight Control −0.001 0.006 0.84
Gynecologic −0.001 0.001 0.91
Urinary Incontinence −0.001 0.001 0.90
Pain/Fatigue −0.001 0.002 0.57
1:

P-value of the relevant factor in a hierarchical linear models of adherence ratio with study timepoint as the only other covariate,

Abbreviations: AET – adjuvant endocrine therapy; ART – antiretroviral therapy; BC – breast cancer; BMQ – Beliefs About Medication Questionnaire; CASE-Cancer – Communication and Attitudinal Self-Efficacy scale; CES-D – Center for Epidemiological Studies Depression Scale; GAD-7 – Generalized Anxiety Disorder 7-Item Scale; HELT-LL – Health Literacy Test for Limited Literacy populations; HER2 -human epidermal growth factor receptor 2; PSS – Perceived Stress Scale; SSSS – Sources of Social Support Scale