Table 2.

Immune cell distributions per cohort, expressed as % of total cell counts per biopsy

Median (Range) in %	GSE36059 (n=403)	GSE147089 (n=224)	GSE21374 (n=282)	Combined Dataset 1 GSE147089+GSE147089 (n=596)	Combined Dataset 2 GSE21374+GSE147089 (n=506)
B cells	2.1 (0.1–19.6)	1.3 (0.4–13.0)	2.3 (0.0–15.3)	1.6 (0.1–19.6)	1.5 (0.0–15.3)
CD14+ mono/macro	3.0 (0.1–21.4)	2.3 (0.0–25.5)	3.2 (0.0–19.5)	2.8 (0.0–25.5)	2.8 (0.0–25.5)
CD4mem	11.1 (0.0–30.5)	7.7 (0.0–39.6)	12.7 (0.0–37.1)	9.9 (0.0–30.5)	10.1 (0.0–39.6)
CD4naive	0.0 (0.0–9.8)	0.0 (0.0–11.9)	0.0 (0.0–17.6)	0.0 (0.0–11.9)	0.0 (0.0–17.6)
CD8eff	1.3 (0.0–33.8)	5.5 (0.0–23.1)	0.3 (0.0–26.1)	2.4 (0.0–33.8)	2.4 (0.0–26.1)
CD8effmem	0.3 (0.0–25.4)	0.0 (0.0–8.4)	0.0 (0.0–21.9)	0.0 (0.0–25.4)	0.0 (0.0–21.9)
CD8temra	1.5 (0.1–9.6)	2.0 (0.2–5.5)	1.4 (0.0–7.4)	1.6 (0.1–9.6)	1.7 (0.0–7.4)
FCGR3A+ myeloid	0.9 (0.0–10.1)	0.8 (0.0–18.9)	0.8 (0.0–11.0)	0.8 (0.0–10.6)	0.8 (0.0–18.9)
NK cells	2.9 (0.5–7.1)	2.0 (0.0–9.8)	4.2 (0.5–10.6)	2.5 (0.0–8.6)	3.3 (0.0–10.6)
Total immune cells	28.1 (10.5–85.0)	25.6 (12.8–78.7)	29.9 (11.3–82.9)	27.3 (10.5–85.0)	27.8 (11.3–82.9)

Density plots per cell type per cohort are provided in Supplemental Figure 1.