Table 2. Stratification analysis for association of XPC and XPD genotypes with hepatoblastoma susceptibility in Eastern Chinese children.
| Variables |
XPC rs2229090 (case/control) (n) |
AOR (95% CI)a |
Pa |
XPD rs3810366 (case/control) (n) |
AOR (95% CI)a |
Pa |
XPD
rs238406 (case/control) (n) |
AOR (95% CI)a |
Pa | |||
| GG | GC/CC | GG | GC/CC | GG | GT/TT | |||||||
| AOR, adjusted odds ratio; 95% CI, 95% confidence interval. a, adjusted for age and sex, omitting the corresponding stratify factor. | ||||||||||||
| Age (month) | ||||||||||||
| <17 | 39/152 | 66/217 | 1.19 (0.76−1.86) | 0.455 | 21/113 | 84/256 | 1.77 (1.04−2.99) | 0.034 | 38/106 | 67/263 | 0.71 (0.45−1.12) | 0.143 |
| ≥17 | 25/176 | 63/228 | 1.95 (1.18−3.22) | 0.010 | 16/101 | 72/302 | 1.49 (0.83−2.69) | 0.180 | 34/118 | 54/285 | 0.66 (0.41−1.06) | 0.085 |
| Sex | ||||||||||||
| Female | 22/136 | 56/187 | 1.84 (1.07−3.17) | 0.027 | 19/88 | 59/234 | 1.19 (0.67−2.10) | 0.562 | 29/96 | 49/226 | 0.71 (0.42−1.20) | 0.199 |
| Male | 42/192 | 73/258 | 1.30 (0.85−1.99) | 0.222 | 18/126 | 97/324 | 2.17 (1.26−3.75) | 0.005 | 43/128 | 72/322 | 0.67 (0.43−1.02) | 0.063 |
| Clinical stages | ||||||||||||
| I+II | 34/328 | 76/445 | 1.65 (1.07−2.54) | 0.022 | 20/214 | 90/558 | 1.78 (1.07−2.98) | 0.027 | 44/224 | 66/548 | 0.61 (0.40−0.92) | 0.020 |
| III+IV | 18/328 | 43/445 | 1.76 (1.00−3.10) | 0.052 | 13/214 | 48/558 | 1.41 (0.75−2.66) | 0.289 | 20/224 | 41/548 | 0.84 (0.48−1.47) | 0.538 |