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. 2024 Jun 30;36(3):298–305. doi: 10.21147/j.issn.1000-9604.2024.03.06

Table 2. Stratification analysis for association of XPC and XPD genotypes with hepatoblastoma susceptibility in Eastern Chinese children.

Variables XPC rs2229090
(case/control) (n)
AOR
(95% CI)a
Pa XPD rs3810366
(case/control) (n)
AOR
(95% CI)a
Pa XPD
rs238406
(case/control) (n)
AOR
(95% CI)a
Pa
GG GC/CC GG GC/CC GG GT/TT
AOR, adjusted odds ratio; 95% CI, 95% confidence interval. a, adjusted for age and sex, omitting the corresponding stratify factor.
Age (month)
 <17 39/152 66/217 1.19 (0.76−1.86) 0.455 21/113 84/256 1.77 (1.04−2.99) 0.034 38/106 67/263 0.71 (0.45−1.12) 0.143
 ≥17 25/176 63/228 1.95 (1.18−3.22) 0.010 16/101 72/302 1.49 (0.83−2.69) 0.180 34/118 54/285 0.66 (0.41−1.06) 0.085
Sex
 Female 22/136 56/187 1.84 (1.07−3.17) 0.027 19/88 59/234 1.19 (0.67−2.10) 0.562 29/96 49/226 0.71 (0.42−1.20) 0.199
 Male 42/192 73/258 1.30 (0.85−1.99) 0.222 18/126 97/324 2.17 (1.26−3.75) 0.005 43/128 72/322 0.67 (0.43−1.02) 0.063
Clinical stages
 I+II 34/328 76/445 1.65 (1.07−2.54) 0.022 20/214 90/558 1.78 (1.07−2.98) 0.027 44/224 66/548 0.61 (0.40−0.92) 0.020
 III+IV 18/328 43/445 1.76 (1.00−3.10) 0.052 13/214 48/558 1.41 (0.75−2.66) 0.289 20/224 41/548 0.84 (0.48−1.47) 0.538