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. 2024 Jun 25;3:1336887. doi: 10.3389/fnimg.2024.1336887

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Copyright © 2024 Shahdloo, Khalighinejad, Priestley, Rushworth and Chiew.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Off-resonance correction, and the experimental paradigm. (A, B) EPI reference navigators in each frame are compared to a reference frame to estimate the dynamic linear off-resonance. These estimates are then used to correct the imaging data (Shahdloo et al., 2022). (C) This off-resonance correction method was validated in a decision-making task in awake NHPs, where the animals decide to act based on the number and color of dots appearing on the screen, respond by touching a pad, and receive a liquid reward based on the response. The experimental paradigm involves a wide range of body motion, as well as irregular events.