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. 2024 Jul 9;15(7):486. doi: 10.1038/s41419-024-06884-3

Fig. 6. Diagrammatical image illustrates the facilitating role of caspase-3 in oncogenic transformation.

Fig. 6

Oncogene stress-induced caspase-3 activation triggers the translocation of EndoG from mitochondria, which migrates to the nucleus, thereby induces phosphorylation of Src-STAT3 signaling pathway to facilitate oncogenic transformation.