Treatment of ER-positive/HER2-negative ABC
Legend: ABC, advanced breast cancer; AI, aromatase inhibitor; CDK, cyclin-dependent kinase; DFI, disease-free interval; ER, oestrogen receptor; HER2, human epidermal growth factor receptor 2; PIK3CA, phosphatidylinositol-4,5-biphosphate 3-kinase catalytic subunit alpha. a Rechallenge with a taxane or anthracycline is possible if cumulative dose not reached and DFI ≥12 months.