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. 2024 Jun 27;15(3):1224–1244. doi: 10.21037/jgo-24-425

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2024 Journal of Gastrointestinal Oncology. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Correlation between MMP11 expression and immunoinhibitors and MHC. (A) Correlation between MMP11 and immunoinhibitors in tumors by heatmap analysis. (B) MMP11 expression was correlated with the immunostimulators ADORA2A, CD160, HAVCR2, KDR, LGALS9, PDCD1LG2, PVRL2, TGFB1, and TGFBR1. (C) Correlation between MMP11 and MHC molecule in tumors by heatmap analysis. (D) MMP11 expression was positively correlated with the MHC molecules B2M, HLA-A, HLA-B, HLA-C, HLA-DQA2, HLA-F, TAP1, TAP2, and TAPBP in PAAD. PAAD, pancreatic adenocarcinoma; MMP11, matrix metalloproteinase 11; MHC, major histocompatibility complex.