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. 2024 Jun 27;15(3):1224–1244. doi: 10.21037/jgo-24-425

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2024 Journal of Gastrointestinal Oncology. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Correlation between MMP11 expression and TILs. (A) Heatmap analysis of the correlation between MMP11 and TILs in tumors. (B) MMP11 expression was significantly positively associated with the infiltrating levels of Tcm_CD8, Tem_CD8, Tcm_CD4, Tfh, Tgd, Th1, Th2, Treg, NK, CD56bright, CD56dim, MDSC, NKT, Act_DC, pDC, macrophages and eosinophil in PAAD, and was negatively corelated with the infiltrating levels of eosinophils in PAAD. Treg, regulatory T cell; NK, natural killer; MDSC, myeloid-derived suppressor cell; NKT, natural killer T cell; pDC, plasmacytoid dendritic cell; iDC, interdigitatingcell dendritic cell; PAAD, pancreatic adenocarcinoma; MMP11, matrix metalloproteinase 11; TILs, tumor-infiltrating lymphocytes; NK, natural killer.