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. 2024 Jun 10;24(4):469–479. doi: 10.1007/s40256-024-00652-6

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 3 — Proposed algorithm for the use of vericiguat in older and complex patients. ARNI angiotensin receptor/neprilysin inhibitor, BB β-blockers, HF heart failure, HFrEF heart failure with reduced ejection fraction, MRA mineralocorticoid receptor antagonist, OMT optimal medical therapy, PDE-5 phosphodiesterase-5, RASi renin-angiotensin-aldosterone system inhibitors, SBP systolic blood pressure, SGLT2i sodium-glucose co-transporter-2 inhibitors, UTI urinary tract infection, WRF worsening renal function