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. 2024 May 21;39(5):895–907. doi: 10.1007/s11011-024-01345-4

Fig. 2.

Fig. 2

Overexpression of hsa_circ_0004872 inhibited proliferation, migration, and invasion of meningiomas cells through suppressing PD-L1. A The expression of hsa_circ_0004872 in IOMM‐ Lee and CH157-MN cells with pcDNA3.1 or pcDNA3.1-circ transfection was evaluated by RT-qPCR. B, C The mRNA and protein expression of PD-L1 in IOMM‐ Lee and CH157-MN cells with pcDNA3.1 or pcDNA3.1-PD-L1 transfection was determined by RT-qPCR and western blot. D Cell viability of IOMM‐ Lee and CH157-MN cells was detected by CCK8 assay after hsa_circ_0004872 overexpression with/without PD-L1 cooverexpression. E, F Cell migration and invasion measured using Transwell assay upon hsa_circ_0004872 overexpression with/without PD-L1 co-overexpression. *P < 0.05. **< 0.01