Extended Data Fig. 9 |. Adversarial autoencoder (AAE) based model for anchor-free generation of scRNA-seq from Raman profiles.

Top: Two autoencoders (AEs) – one for Raman and the other for scRNA-seq – are trained adversarially to learn two indistinguishable latent spaces. Once a common latent space is found, new Raman spectra are encoded using the encoder part of the Raman AE and decoded to scRNA-seq using the decoder part of the scRNA-seq AE (bottom).