. 2024 Jun 26;12:1383065. doi: 10.3389/fpubh.2024.1383065

Table 3.

The mediating effect of FIB-4 on the association between OPA and blood pressure in different lifestyle groups.

M	W	Y	Exposure to the mediator (β_exposure)	Mediator to outcome (γ_M)	Mediated effect (Indirect effect, β_exposure × γ_M)	Direct effect (γ_exposure)	Mediated proportion (%)
FIB-4	Non-smoking	SBP	0.30 (0.23, 0.38)^*	7.39 (4.19, 10.58)^*	2.25 (1.16, 3.57)^*	2.43 (−0.74, 5.60)	–
	Non-smoking	DBP	0.30 (0.23, 0.38)^*	1.90 (−0.15, 3.95)	0.58 (−0.03, 1.35)	1.16 (−0.87, 3.18)	–
	Smoking	SBP	0.22 (0.12, 0.33)^*	10.12 (6.88, 13.35)^*	2.25 (1.15, 3.68)^*	4.69 (1.08, 8.29)^*	32.42%
	Smoking	DBP	0.22 (0.12, 0.33)^*	5.86 (3.69, 8.05)^*	1.30 (0.63, 2.28)^*	1.90 (−0.54, 4.34)	–
	No-drinking alcohol	SBP	0.31 (0.23, 0.39)^*	6.96 (4.06, 9.85)^*	2.15 (1.16, 3.35)^*	2.90 (−0.04, 5.84)	–
	No-drinking alcohol	DBP	0.31 (0.23, 0.39)^*	2.05 (0.17, 3.93)^*	0.63 (0.02, 1.32)^*	1.26 (−0.65, 3.16)	–
	Drinking alcohol	SBP	0.18 (0.06, 0.29)^*	11.17 (7.47, 14.86)^*	1.98 (0.73, 3.64)^*	4.24 (0.22, 8.26)^*	31.83%
	Drinking alcohol	DBP	0.18 (0.07, 0.29)^*	6.42 (3.95, 8.89)^*	1.14 (0.46, 2.17)^*	2.05 (−0.64, 4.73)	–
	Bland diet	SBP	0.24 (0.10, 0.38)^*	5.74 (1.19, 10.29)^*	1.36 (0.39, 3.22)^*	5.37 (0.62, 10.11)^*	20.21%
	Bland diet	DBP	0.24 (0.10, 0.38)^*	1.81 (−1.22, 4.85)	0.43 (−0.29, 1.58)	2.56 (−0.61, 5.72)	–
	No-bland diet	SBP	0.28 (0.21, 0.35)^*	9.24 (6.59, 11.88)^*	2.57 (1.65, 3.70)^*	2.77 (0.06, 5.49)^*	48.13%
	No-bland diet	DBP	0.28 (0.21, 0.35)^*	4.16 (2.42, 5.89)^*	1.16 (0.64, 1.83)^*	1.21 (−0.57, 2.99)	–

OPA, occupational physical activity; FIB-4, fibrosis index based on the four factors.

Mediator M is fibrosis index based on the four factors, Y means the dependent variable, and W represents the moderator. The results were adjusted for age, sex, body mass index, and job seniority.

^*P < 0.05.