Table 4.
The mediating effect of APRI on the association between OPA and blood pressure in different lifestyle groups.
| M | W | Y | Exposure to the mediator (βexposure) | Mediator to outcome (γM) | Mediated effect (Indirect effect, βexposure × γM) | Direct effect (γexposure) | Mediated proportion (%) |
|---|---|---|---|---|---|---|---|
| APRI | Non-smoking | SBP | 0.06 (−0.01, 0.12) | 1.06 (−2.74, 4.87) | 0.06 (−0.12, 0.51) | 4.61 (1.53, 7.69)* | – |
| DBP | 0.06 (−0.01, 0.12) | −0.77 (−3.17, 1.63) | −0.04 (−0.29, 0.07) | 1.78 (−0.16, 3.72) | – | ||
| Smoking | SBP | 0.03 (−0.07, 0.13) | 4.31 (0.66, 7.95)* | 0.12 (−0.28, 0.75) | 6.82 (3.15, 10.49)* | – | |
| DBP | 0.03 (−0.07, 00.13) | 2.69 (0.25, 5.13)* | 0.07 (−0.20, 0.51) | 3.13 (0.67, 5.59)* | – | ||
| No-drinking alcohol | SBP | 0.07 (0.00, 0.13)* | 0.90 (−2.58, 4.38) | 0.06 (−0.14, 0.47) | 4.99 (2.14, 7.85)* | – | |
| DBP | 0.07 (0.00, 0.13)* | −0.73 (−2.96, 1.50) | −0.05 (−0.30, 0.08) | 1.94 (0.11, 3.77)* | – | ||
| Drinking alcohol | SBP | −0.02 (−0.13, 0.08) | 4.62 (0.54, 8.69)* | −0.10 (−0.96, 0.32) | 6.32 (2.19, 10.45)* | – | |
| DBP | −0.02 (−0.13, 0.08) | 3.13 (0.44, 5.82)* | −0.07 (−0.72, 0.19) | 3.25 (0.53, 5.98)* | – | ||
| Bland diet | SBP | 0.05 (−0.07, 0.17) | 1.63 (−3.72, 6.99) | 0.08 (−0.19, 0.93) | 6.64 (1.95, 11.33)* | – | |
| DBP | 0.05 (−0.07, 0.17) | −1.44 (−4.97, 2.09) | −0.08 (−0.63, 0.10) | 3.06 (−0.03, 6.16) | – | ||
| No-bland diet | SBP | 0.04 (−0.03, 0.10) | 2.77 (−0.28, 5.82) | 0.10 (−0.05, 0.45) | 5.24 (2.55, 7.93)* | – | |
| DBP | 0.04 (−0.03, 0.10) | 1.59 (−0.38, 3.55) | 0.06 (−0.03, 0.28) | 2.31 (0.57, 4.04)* | – |
OPA, occupational physical activity; APRI, aspartate aminotransferase to platelet ratio index.
Mediator M is the aspartate aminotransferase to platelet ratio index, Y means the dependent variable, and W represents the moderator. The results were adjusted for age, sex, body mass index, and job seniority.
*P < 0.05.