Table 5.
The mediating effect of AAR on the association between OPA and blood pressure in different lifestyle groups.
| M | W | Y | Exposure to the mediator (βexposure) | Mediator to outcome (γM) | Mediated effect (Indirect effect, βexposure × γM) | Direct effect (γexposure) | Mediated proportion (%) |
|---|---|---|---|---|---|---|---|
| AAR | Non-smoking | SBP | 0.11 (0.06, 0.17)* | −3.03 (−7.51, 1.44) | −0.34 (−0.98, 0.08) | 5.01 (1.91, 8.12)* | – |
| DBP | 0.11 (0.06, 0.17)* | −4.60 (−7.41, −1.80) | −0.52 (−1.04, −0.18) | 2.25 (0.30, 4.20)* | – | ||
| Smoking | SBP | 0.15 (0.07, 0.22)* | 4.55 (−0.22, 9.33) | 0.66 (0.06, 1.72)* | 6.27 (2.53, 10.02)* | – | |
| DBP | 0.15 (0.07, 0.22)* | 4.71 (1.53, 7.89)* | 0.69 (0.21, 1.51)* | 2.52 (0.03, 5.01)* | 21.50% | ||
| No-drinking alcohol | SBP | 0.12 (0.06, 0.17)* | −2.11 (−6.35, 2.12) | −0.25 (−0.83, 0.17) | 5.30 (2.41, 8.19)* | – | |
| DBP | 0.12 (0.06, 0.17)* | −3.02 (−5.72, −0.32) | −0.35 (−0.83, −0.07) | 2.24 (0.40, 4.09)* | – | ||
| Drinking alcohol | SBP | 0.15 (0.06, 0.23)* | 4.05 (−1.10, 9.19) | 0.60 (−0.04, 1.62) | 5.62 (1.41, 9.83)* | – | |
| DBP | 0.15 (0.06, 0.23)* | 3.30 (−0.09, 6.69) | 0.49 (0.05, 1.22)* | 2.69 (−0.08, 5.47) | – | ||
| Bland diet | SBP | 0.10 (0.01, 0.18)* | −4.47 (−12.06, 3.11) | −0.44 (−1.56, 0.14) | 7.17 (2.43, 11.90)* | – | |
| DBP | 0.10 (0.01, 0.18)* | −0.58 (−5.60, 4.43) | −0.06 (−0.64, 0.52) | 3.05 (−0.09, 6.18) | – | ||
| No-bland diet | SBP | 0.14 (0.09, 0.20)* | 0.98 (−2.68, 4.64) | 0.14 (−0.31, 0.65) | 5.20 (2.46, 7.95)* | – | |
| DBP | 0.14 (0.09, 0.20)* | −0.63 (−2.99, 1.73) | −0.09 (−0.46, 0.26) | 2.45 (0.69, 4.22)* | – |
OPA, occupational physical activity; AAR, aspartate aminotransferase to alanine aminotransferase ratio.
Mediator M is the aspartate aminotransferase to alanine aminotransferase ratio, Y means the dependent variable, and W represents the moderator. The results were adjusted for age, sex, body mass index, and job seniority.
*P < 0.05.