Fig. 5.

Combination of clinical and CD3ML models. a) Bar plots of time-dependent Area Under the Curve (AUC) for clinical, CD3ML and clinical + CD3ML models for disease-free survival, ∗∗p < 0.01 and ∗∗∗p < 0.001. Kaplan–Meier curves with patients stratified according to clinical and CD3ML status for disease-free survival in the b) training cohort, c) internal validation cohort and d) external validation cohort. e) Kaplan–Meier curves with patients stratified according to the combined, 3-modalities model for disease-free survival in all patients. Hazard ratio and log-rank test p-value were shown when proportional hazards assumption was verified otherwise the RMST measure and p-value were shown.