Figure 4.

RNA-seq combined with H3K9la MNase ChIP-seq and proteomics analysis in KYSE30 cells cultured in hypoxia

(A) Volcano map presents that 1110 mRNAs were upregulate and 402 mRNA were down-regulate in hypoxia group (p adjust<0.05, |Log₂FC|>1).

(B) GO enrichment analysis of differentially expressed genes in KYSE30 cells cultured in normoxia and hypoxia.

(C) 260 genes were observed in an overlapped combination of differentially expressed genes and H3K9la binding different peaks in KYSE30 cells cultured in normoxia and hypoxia.

(D) GO enrichment analysis of the overlapped genes.