TABLE 1.
Tunicamycin treatment of rodent cells enables their infection by RD114 and simian type D retrovirusesa
| Cell line | Titer of LacZ pseudotype (CFU/ml)
|
|||||
|---|---|---|---|---|---|---|
| RD114
|
SRV-2
|
BaEV
|
||||
| − Tunic | + Tunic | − Tunic | + Tunic | − Tunic | + Tunic | |
| NIH 3T3 | 7 | 4.8 × 104 | 21 | 2.2 × 103 | 9.4 × 103 | 2.6 × 104 |
| Rat208F | 1.4 × 102 | 1.8 × 105 | − | − | 1.4 × 105 | 1.2 × 105 |
a
Mouse NIH 3T3 and Rat208F cells were tested for their susceptibilities to LacZ(RD114), LacZ(SRV-2), and LacZ(BaEV) pseudotype viruses before treatment with tunicamycin (−Tunic) and after treatment with 125 ng of tunicamycin/ml (+Tunic). The titers are averages of two experiments. Titers of SRV-2 on Rat208F cells were not determined, as indicated by the dashes.