Table 3.
The gender-associated (expressed highly in the associated gender) proteomic profile of adult Schistosoma spp.
| Genes/Proteins | Adult female worms | Adult male worms | Reference |
|---|---|---|---|
| Gender associated | Epididymal secretory protein E1 | Gynecophoral canal protein | [129,134] |
| Female-specific 800 protein Tyrosinases 1 and 2 | |||
| Eggshell proteins (p14, p19, p34, p48, chorion, etc.) | |||
| Cytoskeleton and motor proteins | Actin 2 | [135] | |
| Troponins | |||
| Dynein light chain 3 | |||
| Myosin | |||
| Myosin regulatory light chain | |||
| Paramyosin | |||
| Tropomyosin | |||
| Alpha-actinin ′ | |||
| Fimbrin | |||
| Microtubule associated protein 1B | |||
| Desmoyokin | |||
| Transporters | SGPT2 | ||
| Fatty acid-binding protein | |||
| Nutrient associated | Ferritin-1 heavy chain | Cathepsin B | [135,136] |
| Cathepsin D | |||
| Adenylosuccinate lyase | |||
| Growth associated | Elongation factor 1-alpha | [135] | |
| Polo-like kinase1 | |||
| Ribosomal proteins Translationally controlled tumor protein | |||
| Stathmin-like protein | |||
| Redox associated | Superoxide dismutase (SOD) | 28 kDa glutathione-S-transferase | [135] |
| Glutathione peroxidase Extracellular superoxide dismutase | |||
| Calcium signalling | Calponin | [135] | |
| Calpain | |||
| Tegument associated | Sj25, Sm23, Sm8, Sm15, Sm20 | [96,135] | |
| 22.6kD tegumental antigen | [137] | ||
| Membrane associated | 23K integral membrane protein (SJ23) | Annexin | [135] |
| Annexin B13a | Collagens | ||
| Vesicular integral membrane protein Vip36 | Extensin class I | ||
| CD36 antigen | Echinonectin | ||
| Tetraspanin | |||
| Immune associated | Cyclophilin B | [135] | |
| Immunophilin | |||
| Mucin-like protein | |||
| Others | sm16 | 14-3-3 protein | [136] |
| Histidine-rich proteins Asparagine-rich proteins |